project - EIP-AGRI Operational Group
Using meat by-products to obtain bioactive hydrolysates with antimicrobial properties (BIOPEPTIDES)
Aprovechamiento de subproductos cárnicos para la obtención de hidrolizados bioactivos con propiedades antimicrobianas (BIOPEPTIDS)
Context
Antibiotics are drugs used in both human and veterinary medicine for the treatment and prophylaxis of infectious diseases caused by bacteria. Although the first antibiotics were discovered less than 90 years ago, it was not until the 1940s that they were widely used for the treatment of infections. Therapeutic use of antibiotics as a disease control measure is one of the most important achievements in medicine, helping reduce mortality and morbidity from bacterial diseases. Over the years, in both human and veterinary medicine, antibiotics have been susceptible to incorrect and indiscriminate use, producing a negative impact on individual and public health, as well as the resulting emergence of antimicrobial resistance. This has led to the search for new alternatives.
Objectives
The main objective of this project is to obtain new protein hydrolysates from different meat industry by-products with antimicrobial activity. It also considers identifying the peptides responsible for the antimicrobial effect in the hydrolysate with the greatest potential.
Objectives
Con todo ello, el objetivo principal de este proyecto es la obtención de nuevos hidrolizados proteicos a partir de distintos subproductos de la industria cárnica con actividad antimicrobiana. Se plantea también la identificación de los péptidos responsables del efecto antimicrobiano del hidrolizado que presente mayor potencial.
Activities
• Selecting and characterising raw materials for the production of hydrolysates
• Processing hydrolysates
• Pre-selection of protein by functionality
• Characterising the selected hydrolysates
• Stability of protein hydrolysates functionalities during gastrointestinal transit
• Prioritising pre-selected protein hydrolysates
• Hydrolysate production at the pilot plant
• Identifying the most common peptides
• Determining the bioactivity of selected peptides
• Demonstrating in vitro efficacy of the selected protein hydrolysate
• Characterising and assessing the digestibility of the waste generated in producing the selected hydrolysate
• Patentability
• Dissemination of the project
Activities
• Selección y caracterización de las materias primas
• Elaboración y preselección de los hidrolizados
• Caracterización de los hidrolizados seleccionados
• Estabilidad de las funcionalidades de los hidrolizados proteicos durante el tránsito gastrointestinal
• Jerarquización de los hidrolizados proteicos pre-seleccionados
• Elaboración del hidrolizado a nivel de planta piloto
• Identificación y determinación de la bioactividad de los péptidos mayoritarios del hidrolizado seleccionado
• Demostración de la eficacia in vitro del hidrolizado proteico seleccionado
• Caracterización y evaluación de la digestibilidad de los residuos generados
• Patentabilidad y difusión del proyecto
Project details
- Main funding source
- Rural development 2014-2020 for Operational Groups
- Rural Development Programme
- 2014ES06RDRP009 Spain - Rural Development Programme (Regional) - Cataluña
Location
- Main geographical location
- Barcelona
- Other geographical location
- Tarragona, Girona
EUR 196392.98
Total budget
Total contributions from EAFRD, national co-financing, additional national financing and other financing.
Contacts
Project coordinator
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Eudald Casas
Project coordinator